Risk is a pathway
Heart attack and stroke often emerge from connected steps, not one isolated switch. Plaque, inflammation, rupture, clot, and tissue injury can build on one another.
Risk Atlas · cascade
How separate risk processes can connect into an event pathway.
This risk atlas links the previous modules into one simplified sequence: plaque context, inflammatory activity, rupture, clot formation, and flow restriction. Use the slider to see how a local artery problem can connect into a pathway that can lead toward downstream event modules without claiming that one step automatically causes the next.
Cascade visualisation
Pathway view reveals risk layers, amplifier arrows, and hand-off cues without changing the stage.
Connected risk layers
Key information
Cascade: what to understand
Each step has different levers
Different interventions work at different steps: statins and lifestyle at the plaque stage, anti-inflammatory approaches at the inflammation stage, and antiplatelet or anticoagulant therapy when clinically appropriate at the clot stage.
Earlier action gives more options
The farther downstream the cascade goes, the more urgent and limited the choices become. Prevention is powerful because it acts before the emergency stage.
Risk factors interact
ApoB, Lp(a), blood pressure, smoking, diabetes, kidney disease, and family history can combine. The combined pattern may matter more than any single number.
Cascade thinking improves questions
Instead of asking only “is my cholesterol normal?”, ask where risk could be entering the pathway. That makes hidden risk easier to discuss.
Events are not random
Many cardiovascular events feel sudden but develop from upstream biology over time. The cascade makes that hidden buildup easier to see.
One normal test does not close the pathway
A normal result can be reassuring for the question it answers. It does not automatically answer every upstream or downstream risk question.
The cascade is not destiny
Showing the pathway does not mean the pathway must complete. The point is to find places where risk can be clarified and reduced.
Do not self-treat a cascade stage
The atlas explains where decisions may occur. It does not tell you which medicines or tests you personally need.
Heart risk products
Clarify risks. Navigate dangers. Prevent events.
Cascade is where separate risk signals start to matter together. If you want help understanding what your current heart risk checks do and do not show, start with Clarify. If you already have several signals and want to understand how they may interact in a pathway, Navigate may be right for you. If you want to reduce your — or a loved one’s — risk of heart attack, stroke, or avoidable cardiovascular damage, Prevent may be right for you.